Symptoms of EPI are similar to other GI conditions

Other GI conditions like celiac disease, irritable bowel syndrome (IBS), Crohn’s disease, ulcerative colitis, and small intestinal bacterial overgrowth (SIBO), can have overlapping symptoms with EPI, which makes diagnosing EPI difficult.2-6

The symptoms of EPI may include frequent diarrhea, unexplained weight loss, steatorrhea, gas, bloating, and abdominal pain. If your patient is experiencing one or more of these symptoms, it could be EPI.2,3

References: 1. Centers for Medicare & Medicaid Services. ICD-10-CM tabular list of diseases and injuries. 2017 codes tables and index. Accessed August 20, 2016. 2. Fieker A, Philpott J, Armand M. Enzyme replacement therapy for pancreatic insufficiency: present and future. Clin Exp Gastroenterol. 2011;4:55-73. 3. Dominguez-Muñoz JE. Pancreatic enzyme therapy for pancreatic exocrine insufficiency. Curr Gastroenterol Rep. 2007;9(2):116-122. 4. Signs & symptoms of celiac disease. Celiac Support Association website. Accessed August 11, 2016. 5. Longo DL, Fauci AS, Kasper DL, et al, eds. Harrison’s Principles of Internal Medicine. 18th ed. New York, NY: McGraw-Hill; 2012. 6. Bacterial overgrowth syndrome. The Merck Manual website. Accessed August 11, 2016.