Clinically relevant maldigestion may occur earlier than the appearance of overt symptoms of EPI. Symptoms may not present until pancreatic damage is advanced. There may be significant maldigestion and malabsorption in patients without the classic clinical sign of steatorrhea.
Steatorrhea is defined as >7 g of fecal fat per day while eating a diet with 100 g/day of fat. Steatorrhea occurs when pancreatic function is ≤10% of normal output. Due to excess fat content in the stool, patients with steatorrhea will report bowel movements that are loose, floating, oily, and hard to flush.
Symptoms of EPI may include1-3:
Patients with EPI may present with signs and symptoms similar to some GI conditions or diseases. If your patient presents with one or more symptoms, consider EPI in your differential diagnosis.1,5
Select a condition below to
see the shared symptoms.
*Steatorrhea: >7 g of fecal fat per day while consuming 100 g of dietary fat per day.